Peptic Ulcer Disease

Peptic-Ulcer-Disease

Peptic ulcer disease is a medical condition characterized by the formation of open sores within the lining of the stomach, small intestine, or lower esophagus. These ulcers can lead to discomfort and complications if left untreated.

Types of Peptic Ulcers:

  1. Gastric Ulcers:
    • Located inside the stomach.
  2. Duodenal Ulcers:
    • Develop in the upper portion of the small intestine known as the duodenum.


Causes:
Peptic ulcers can be attributed to various factors, including:

  • H. pylori Bacteria: Commonly associated with peptic ulcer development.
  • Prolonged Use of Medications: Such as aspirin and non-steroidal anti-inflammatory drugs (NSAIDs).
  • Lifestyle Habits: Smoking, alcohol consumption, and stress can exacerbate ulcer symptoms.
  • Dietary Factors: Spicy foods may worsen peptic ulcers.


Symptoms:
Manifestations of peptic ulcers often include:

  • Burning pain in the stomach.
  • Heartburn.
  • Nausea and indigestion.
  • Weight loss and loss of appetite.


Diagnosis:
Diagnostic procedures utilized for peptic ulcer detection include:

  • Laboratory Tests: Blood, stool, or breath tests to detect the presence of H. pylori bacteria.
  • Endoscopy: Involves the insertion of an endoscope to visualize the digestive tract and collect tissue samples for analysis.
  • Upper Gastrointestinal (GI) Series: Barium swallow procedure followed by X-rays to identify ulcers and abnormalities in the upper digestive system.


Treatment:
Treatment modalities for peptic ulcers encompass:

  • Antibiotics: Prescribed to eradicate H. pylori bacteria.
  • Acid Blocker Medications: Such as ranitidine and famotidine to reduce stomach acid production.
  • Mucosal Protective Medications: Sucralfate and misoprostol are administered to protect the lining of the digestive tract.
  • Antacids: Offered to neutralize stomach acid and alleviate pain.


Complications:
Untreated peptic ulcers may lead to serious complications such as:

  • Perforation of the digestive tract.
  • Internal bleeding.
  • Scarring of tissue, hindering food passage.
  • Refractory ulcers requiring alternative treatment approaches.


Risk Factors:
Several risk factors contribute to the development of peptic ulcers, including:

  • Smoking and alcohol consumption.
  • Spicy food consumption.
  • Stressful lifestyles.